| General Information of DME (ID: DME1051) |
| DME Name |
Dihydrofolate reductase (folA), Chlamydia muridarum
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| Synonyms |
DHF reductase; 5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase; Bifunctional TS-DHFR; BmDHFR; Bacterial DFR-TS; Bacterial DHFR; TC_0902; folA
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| Gene Name |
folA
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| UniProt ID |
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| Gene ID |
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| EC Number |
EC: 1.5.1.3 (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
CH-NH donor oxidoreductase
NAD/NADP acceptor oxidoreductase
EC: 1.5.1.3
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| Lineage |
Species: Chlamydia muridarum (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Chlamydiae
Class: Chlamydiia
Order: Chlamydiales
Family: Chlamydiaceae
Genus: Chlamydia
Species: Chlamydia muridarum
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Interactome(loading-time for this interactome depdends on the speed of web connection)
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Interactions between Host Protein and DME (HOSPPI)  Jump to Detailed Interactome Data |
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Tissue Distribution |
Primarily distributed in human gut and vagina.
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| Sequence |
MIQATGIVAIDPRGVMGGAGKLPWNYPEDLRFFSETIQDHPIIMGRKTWESLPDRYKCGR
TVIVFSRQHSCAQGIWISSLVEYEKLSLNSPFLIGGAELFDWFFQYNLLKSCFVTHIKRE
YQGDTFFPVERLSGWKRESVLKTEDFNIYHYENYANQNP
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| Pathway |
Folate biosynthesis (cmu00790 ) |
| Metabolic pathways (cmu01100 ) |
| One carbon pool by folate (cmu00670 ) |
| Function |
This enzyme can slowly reduces folate to 5,6,7,8-tetrahydrofolate in animals and some micro-organisms.
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