| General Information of DME (ID: DME1461) |
| DME Name |
Homoserine-O-transsuccinylase (metAA), Salmonella enterica
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| Synonyms |
Homoserine O-acetyltransferase; Homoserine acetyltransferase; Homoserine transacetylase; HTS-like HTA; HAT; HTA
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| Gene Name |
metAA
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| UniProt ID |
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| EC Number |
EC: 2.3.1.46 (Click to Show/Hide the Complete EC Tree)
Transferase
Acyltransferase
Acyltransferase
EC: 2.3.1.46
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| Lineage |
Species: Salmonella enterica (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Salmonella
Species: Salmonella enterica
Subspecies: Salmonella enterica subsp. enterica serovar Typhimurium
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Interactome(loading-time for this interactome depdends on the speed of web connection)
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Interactions between Xenobiotics and DME (XEOTIC)  Jump to Detailed Interactome Data  |
Interactions between Host Protein and DME (HOSPPI) Jump to Detailed Interactome Data |
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Tissue Distribution |
Primarily distributed in human gut.
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| Sequence |
MPINVPSGLPAVKVLAKEGIFVMTEKRAIHQDIRPLEILILNLMPDKIKTEIQLLRLLGN
TPLQVNVTLLYTETHKPKHTPIEHILKFYTTFSAVKDRKFDGFIITGAPVELLPFEEVDY
WEELTEIMEWSRHNVYSTMFICWAAQAGLYYFYGIPKYELPQKLSGVYKHRVAKDSVLFR
GHDDFFWAPHSRYTEVKKEDIDKVPELEILAESDEAGVYVVANKSERQIFVTGHPEYDRY
TLRDEYYRDIGRNLKVPIPANYFPNDDPTKTPILTWWSHAHLFFSNWLNYCIYQKTPYRL
EDIH
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| Structure |
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| Pathway |
Biosynthesis of amino acids (tma01230 ) |
| Biosynthesis of secondary metabolites (tma01110 ) |
| Cysteine and methionine metabolism (tma00270 ) |
| Metabolic pathways (tma01100 ) |
| Sulfur metabolism (tma00920 ) |
| Function |
This enzyme catalyzes the conversion of L-homoserine to O-succinyl-L-homoserine and takes part in methionine metabolism and sulfur metabolism.
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