| General Information of Drug Metabolite (DM) (ID: DM001291) |
| DM Name |
Glutathione conjugates
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Glutathione reductase (GSR)
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DME0110
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| Reduction - Reduction |
Selenium
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[1] , [2] |
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Thioredoxin reductase TR1 (TXNRD1)
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DME0210
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| Reduction - Reduction |
Selenium
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Selenium |
DR1469
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Approved |
Seborrhoeic dermatitis |
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| References |
| 1 |
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis. 1999 Sep;20(9):1657-66.
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| 2 |
New Insights into Oxidative and Reductive Stress Responses and Their Relation to the Anticancer Activity of Selenium-Containing Compounds as Hydrogen Selenide Donors. Biology (Basel). 2023 Jun 17;12(6):875. doi: 10.3390/biology12060875.
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