| General Information of Drug Metabolite (DM) (ID: DM001292) |
| DM Name |
Selenide
|
| Synonyms |
selenide; selenide ion; 22541-48-6; 9GXT7M8EYS; selenium(2-); selanediide; SE-2; selenide(2-); UNII-9GXT7M8EYS; Selenium, ion (Se2+); SELENIDE (SE2-); SELENIUM ION(2-); CHEMBL4597517; CHEBI:15076; Se(2-); A816696; Q27109021; 22788-28-9
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| Structure |
|
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3D MOL
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2D MOL
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| Pharmaceutical Properties |
Molecular Weight |
78.97 |
Topological Polar Surface Area |
0 |
| Heavy Atom Count |
1 |
Rotatable Bond Count |
0 |
| Hydrogen Bond Donor Count |
0 |
Hydrogen Bond Acceptor Count |
1 |
| PubChem CID |
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| Complexity |
0
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| Formula |
Se-2
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| Canonical SMILES |
[Se-2]
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| InChI |
InChI=1S/Se/q-2
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| InChIKey |
HMUBNCUQSSTAIB-UHFFFAOYSA-N
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| IUPAC name |
selenium(2-)
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Glutathione reductase (GSR)
|
DME0110
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| Reduction - Reduction |
Selenium
|
[1] , [2] |
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Thioredoxin reductase TR1 (TXNRD1)
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DME0210
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| Reduction - Reduction |
Selenium
|
[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Selenium |
DR1469
|
Approved |
Seborrhoeic dermatitis |
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| References |
| 1 |
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis. 1999 Sep;20(9):1657-66.
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| 2 |
New Insights into Oxidative and Reductive Stress Responses and Their Relation to the Anticancer Activity of Selenium-Containing Compounds as Hydrogen Selenide Donors. Biology (Basel). 2023 Jun 17;12(6):875. doi: 10.3390/biology12060875.
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