| General Information of Drug Metabolite (DM) (ID: DM005639) |
| DM Name |
7,12-dioxo-LCA
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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7-Hydroxysteroid dehydrogenase (7-HSDH)
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DMEN287
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| Unclear - Unclear |
Oxolithocholic acid
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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12alpha-hydroxysteroid dehydrogenase (12-HSDH)
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DMEN310
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| Unclear - Unclear |
Oxolithocholic acid
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Oxolithocholic acid |
DR2625
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Investigative |
Discovery agent |
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| References |
| 1 |
Metabolism of oxo-bile acids and characterization of recombinant 12alpha-hydroxysteroid dehydrogenases from bile acid 7alpha-dehydroxylating human gut bacteria. Appl Environ Microbiol. 2018 May 1;84(10). pii: e00235-18.
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