Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM005640)
DM Name	7-oxo-DCA
Structure
Structure	3D MOL is unavailable			2D MOL is unavailable

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
12alpha-hydroxysteroid dehydrogenase (12-HSDH)	DMEN310	7,12-dioxo-LCA	Unclear - Unclear	Oxolithocholic acid	[1]
7-Hydroxysteroid dehydrogenase (7-HSDH)	DMEN287	CA	Unclear - Unclear	Oxolithocholic acid	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Oxolithocholic acid		DR2625	Investigative		Discovery agent

References
1	Metabolism of oxo-bile acids and characterization of recombinant 12alpha-hydroxysteroid dehydrogenases from bile acid 7alpha-dehydroxylating human gut bacteria. Appl Environ Microbiol. 2018 May 1;84(10). pii: e00235-18.

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