| General Information of This Metabolic Reaction (MR) (ID:
MR000099) |
| Formula |
|
| Reactant |
A-estradiol |
Product |
2-methoxyestradiol (2MEOE) |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Catechol O-methyltransferase (COMT)
|
DME Info
|
|
Metabolic Type
|
Conjugation
-
Methylation
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
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| References |
| 1 |
Cytochrome P450-mediated metabolism of estrogens and its regulation in human. Cancer Lett. 2005 Sep 28;227(2):115-24.
|
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