Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000098)
Formula Reactant A-estradiol Product Estradiol-2,3-semiquinone
Reactant Info Product Info
Metabolic Enzyme Protein msp1 (msp1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000099 A-estradiol 2-methoxyestradiol (2MEOE) Conjugation - Methylation A-estradiol [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000097 Estradiol-2,3-semiquinone Estradiol-2,3-quinone Unclear A-estradiol [2]
References
1 2-hydroxyestradiol is a prodrug of 2-methoxyestradiol J Pharmacol Exp Ther. 2004 Jun;309(3):1093-7. doi: 10.1124/jpet.103.062505.
2 Cytochrome P450-mediated metabolism of estrogens and its regulation in human. Cancer Lett. 2005 Sep 28;227(2):115-24.

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