Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000399)
Formula Reactant Bortezomib metabolite M1 Product Bortezomib metabolite M25
Reactant Info Product Info
Metabolic Type Oxidation - Hydoxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000408 Bortezomib Bortezomib metabolite M1 Oxidation - Oxidative Deboronation Bortezomib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000398 Bortezomib metabolite M1 Bortezomib metabolite M26 Oxidation - Hydoxylation Bortezomib [1]
MR000397 Bortezomib metabolite M1 Bortezomib metabolite M3 Hydrolysis - Hydrolysis Bortezomib [1]
MR000400 Bortezomib metabolite M1 Bortezomib metabolite M5 Oxidation - Hydoxylation Bortezomib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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