Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000400)
Formula
SVG example
Hydoxylation
Reactant Bortezomib metabolite M1 Product Bortezomib metabolite M5
Reactant Info Product Info
Metabolic Type Oxidation - Hydoxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000408 Bortezomib Bortezomib metabolite M1 Oxidation - Oxidative Deboronation Bortezomib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000399 Bortezomib metabolite M1 Bortezomib metabolite M25 Oxidation - Hydoxylation Bortezomib [1]
MR000398 Bortezomib metabolite M1 Bortezomib metabolite M26 Oxidation - Hydoxylation Bortezomib [1]
MR000397 Bortezomib metabolite M1 Bortezomib metabolite M3 Hydrolysis - Hydrolysis Bortezomib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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