Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000404)
Formula Reactant Bortezomib metabolite M2 Product Bortezomib metabolite M28
Reactant Info Product Info
Metabolic Type Oxidation - Hydoxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000409 Bortezomib Bortezomib metabolite M2 Oxidation - Oxidation; Deboronation Bortezomib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000405 Bortezomib metabolite M2 Bortezomib metabolite M27 Oxidation - Hydoxylation Bortezomib [1]
MR000402 Bortezomib metabolite M2 Bortezomib metabolite M3 Hydrolysis - Hydrolysis Bortezomib [1]
MR000406 Bortezomib metabolite M2 Bortezomib metabolite M6 Oxidation - Hydoxylation Bortezomib [1]
MR000403 Bortezomib metabolite M2 Bortezomib metabolite M8 Oxidation - Hydoxylation Bortezomib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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