Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000414)
Formula Reactant Bosentan metabolite Ro 64-1056 Product Bosentan metabolite M4
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000413 Bosentan metabolite Ro 47-8634 Bosentan metabolite Ro 64-1056 Oxidation - Methyl-Hydroxylation Bosentan [1]
MR000415 Bosentan metabolite Ro 48-5033 Bosentan metabolite Ro 64-1056 Oxidation - O-Demethylation Bosentan [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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