Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000506)
Formula Reactant R,R-threohydrobupropion Product R,R-threohydrobupropion glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 1A4 (UGT1A4) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000516 Bupropion R,R-threohydrobupropion Reduction - Ketoreduction Bupropion [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000505 R,R-threohydrobupropion R,R-threo-4'-hydroxy-hydrobupropion Oxidation - 4'-Hydroxylation Bupropion [1]
References
1 DrugBank(Pharmacology-Metabolism)Bupropion

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