Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001350)
Formula Reactant Ketoconazole ketone hydroxyl intermediate Product M5 (Ketoconazole)
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001349 Ketoconazole ketone intermediate Ketoconazole ketone hydroxyl intermediate Other reaction - Hydration Ketoconazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001351 Ketoconazole ketone hydroxyl intermediate M2 (Ketoconazole) Oxidation - N-Dealkylation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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