Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001349)
Formula Reactant Ketoconazole ketone intermediate Product Ketoconazole ketone hydroxyl intermediate
Reactant Info Product Info
Metabolic Type Other reaction - Hydration
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001345 Ketoconazole epoxide intermediate Ketoconazole ketone intermediate Oxidation - Oxidation Ketoconazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001351 Ketoconazole ketone hydroxyl intermediate M2 (Ketoconazole) Oxidation - N-Dealkylation Ketoconazole [1]
MR001350 Ketoconazole ketone hydroxyl intermediate M5 (Ketoconazole) Oxidation - Oxidation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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