Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001422)
Formula Reactant Nitroso intermediate Product Lapatinib ditosylate metabolite M2
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001421 N-dealkylated lapatinib Nitroso intermediate Unclear Lapatinib ditosylate [1]
MR001423 N-hydroxy lapatinib Nitroso intermediate Unclear Lapatinib ditosylate [1]
References
1 Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib Drug Metab Dispos. 2011 Jun;39(6):1022-30. doi: 10.1124/dmd.110.037531.

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