Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001815)
Formula
SVG example
Amide Hydrolysis
Reactant Olaparib Product Olaparib metabolite M1
Reactant Info Product Info
Metabolic Type Hydrolysis - Amide Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001814 Olaparib Olaparib metabolite M10 Oxidation - Hydroxylation Olaparib [1]
MR001813 Olaparib Olaparib metabolite M2,M5,M6,M7 Oxidation - Hydroxylation Olaparib [1]
References
1 In vitro metabolism of olaparib in liver microsomes by liquid chromatography/electrospray ionization high-resolution mass spectrometry Rapid Commun Mass Spectrom. 2020 Feb 15;34(3):e8575. doi: 10.1002/rcm.8575.

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