Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001977)
Formula Reactant Pentobarbital Product Pentobarbital carboxylic acid
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001975 Pentobarbital 3'-hydroxypentobarbital Oxidation - Penultimate Oxidation Pentobarbital [1]
MR001974 Pentobarbital 4-hydroxyphenobarbital Oxidation - Hydroxylation Pentobarbital [2]
MR001976 Pentobarbital Phenobarbitone glucoside Conjugation - Glucuronidation Pentobarbital [2]
References
1 American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 2666
2 CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: analysis by population pharmacokinetics. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):821-5.

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