Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002190)
Formula
	Reactant	4'-hydroxypropanolol	Product	Naphthalene-1,4-diol
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002195	Propranolol hydrochloride	4'-hydroxypropanolol	Oxidation - 4-Hydroxylation	Propranolol hydrochloride	[1], [2]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002189	4'-hydroxypropanolol	4-hydroxyalprenolol glucuronide	Conjugation - Glucuronidation	Propranolol hydrochloride	[1], [2]

References
1	Isolation, purification, and structure identification of glucuronic acid conjugates of propranolol and alprenolol and their ring-hydroxylated metabolites Drug Metab Dispos. 1984 Nov-Dec;12(6):749-54.
2	Rapid and simultaneous extraction of propranolol, its neutral and basic metabolites from plasma and assay by high-performance liquid chromatography J Chromatogr. 1985 Oct 11;343(2):349-58. doi: 10.1016/s0378-4347(00)84603-4.

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