Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002278)
Formula Reactant 5-hydroxysulfamethoxazole Product N4-Acetyl-5-OH-sulfamethoxazole
Reactant Info Product Info
Metabolic Enzyme N-acetyltransferase 1 (NAT1) DME Info
N-acetyltransferase 2 (NAT2) DME Info
Metabolic Type Conjugation - Acetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002281 Sulfamethoxazole 5-hydroxysulfamethoxazole Oxidation - 5-Hydroxylation Sulfamethoxazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002279 N-acetylsulfamethoxazole N4-Acetyl-5-OH-sulfamethoxazole Oxidation - 5-Hydroxylation Sulfamethoxazole [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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