General Information of This Metabolic Reaction (MR) (ID: MR002289)
Formula
SVG example
Acetylation
Reactant 5-aminosalicylic acid Product N-acetyl-5-aminosalicylic acid
Reactant Info Product Info
Metabolic Enzyme N-acetyltransferase 1 (NAT1) DME Info
Metabolic Type Conjugation - Acetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009685 Balsalazide 5-aminosalicylic acid Unclear - Unclear Balsalazide [1]
MR010719 Olsalazine Mesalazine Unclear - Unclear Olsalazine [2]
MR002290 Sulfasalazine 5-aminosalicylic acid Unclear Sulfasalazine [3]
References
1 U. S. FDA Label -Balsalazide
2 Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs. 1991 Apr;41(4):647-64.
3 Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population. Clin Chim Acta. 2009 Sep;407(1-2):30-5.

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