Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002290)
Formula
SVG example
Reactant Sulfasalazine Product 5-aminosalicylic acid
Reactant Info Product Info
Metabolic Enzyme Azoreductase (azoR) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002291 Sulfasalazine Sulfapyridine Unclear Sulfasalazine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009685 Balsalazide 5-aminosalicylic acid Unclear - Unclear Balsalazide [2]
MR010719 Olsalazine Mesalazine Unclear - Unclear Olsalazine [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009686 5-aminosalicylic acid N-acetyl mesalazine Unclear - Unclear Balsalazide [2]
MR002289 5-aminosalicylic acid N-acetyl-5-aminosalicylic acid Conjugation - Acetylation Sulfasalazine [1]
References
1 Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population. Clin Chim Acta. 2009 Sep;407(1-2):30-5.
2 U. S. FDA Label -Balsalazide
3 Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs. 1991 Apr;41(4):647-64.

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