Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002295)
Formula
SVG example
O-Glucuronidation
Reactant Indole acetic acid Product Indole-3-Acetic-Acid-O-glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - O-Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002296 Sumatriptan succinate Indole acetic acid Oxidation - Oxidation Sumatriptan succinate [1]
MR009181 Indoleacetaldehyde Indole acetic acid Unclear - Unclear TRYPTAMINE [2], [3]
References
1 Subcutaneous sumatriptan pharmacokinetics: delimiting the monoamine oxidase inhibitor effect. Headache. 2010 Feb;50(2):249-55.
2 Distribution and metabolism of tryptamine in rat brain
3 Tryptamine: a metabolite of tryptophan implicated in various neuropsychiatric disorders

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