Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009181)
Formula
SVG example
Unclear
Reactant Indoleacetaldehyde Product Indole acetic acid
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase 2 (ALDH2) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009180 TRYPTAMINE Indoleacetaldehyde Unclear - Unclear TRYPTAMINE [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002296 Sumatriptan succinate Indole acetic acid Oxidation - Oxidation Sumatriptan succinate [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002295 Indole acetic acid Indole-3-Acetic-Acid-O-glucuronide Conjugation - O-Glucuronidation Sumatriptan succinate [4]
References
1 Distribution and metabolism of tryptamine in rat brain
2 Tryptamine: a metabolite of tryptophan implicated in various neuropsychiatric disorders
3 Subcutaneous sumatriptan pharmacokinetics: delimiting the monoamine oxidase inhibitor effect. Headache. 2010 Feb;50(2):249-55.
4 American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 2666

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