Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002423)
Formula Reactant Trabectedin metabolite M4b Product Trabectedin metabolite M4a
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002428 Trabectedin Trabectedin metabolite M4b Oxidation - Demethylation; Oxidation Trabectedin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002424 Trabectedin metabolite M4b Trabectedin metabolite M16d Oxidation - Oxidation Trabectedin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002425 Trabectedin metabolite M4a Trabectedin metabolite M8c Unclear Trabectedin [1]
References
1 In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping Biochem Pharmacol. 2009 May 15;77(10):1642-54. doi: 10.1016/j.bcp.2009.02.020.

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