Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002438)
Formula
SVG example
Glutathione Conjugation
Reactant Triazolopyridinone epoxide Product Trazodone hydrochloride M3
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002442 Trazodone hydrochloride Triazolopyridinone epoxide Unclear Trazodone hydrochloride [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002437 Triazolopyridinone epoxide Trazodone hydrochloride M2 Unclear Trazodone hydrochloride [1]
MR002439 Triazolopyridinone epoxide Trazodone hydrochloride MQ Unclear Trazodone hydrochloride [1]
References
1 Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4. Chem Biol Interact. 2005 Jun 30;155(1-2):10-20.

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