Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002571)
Formula Reactant Cabazitaxel metabolite M08b Product Cabazitaxel metabolite M02a
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002569 Cabazitaxel metabolite M07 Cabazitaxel metabolite M08b Oxidation - Hydroxylation Cabazitaxel [1]
MR002574 Cabazitaxel metabolite M2 Cabazitaxel metabolite M08b Oxidation - Cleavage Cabazitaxel [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002570 Cabazitaxel metabolite M08b RPR111026 Oxidation - 10-O-Demethylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002572 Cabazitaxel metabolite M02a RPR104943 Oxidation - 10-O-Demethylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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