Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002572)
Formula Reactant Cabazitaxel metabolite M02a Product RPR104943
Reactant Info Product Info
Metabolic Type Oxidation - 10-O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002571 Cabazitaxel metabolite M08b Cabazitaxel metabolite M02a Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002565 RPR111026 RPR104943 Oxidation - Hydroxylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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