Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002784)
Formula
SVG example
Hydroxylation
Reactant Promazine Product 3-hydroxypromazine
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002782 Promazine N-Desmethylpromazine Oxidation - N-Demethylation Promazine [1]
MR002783 Promazine Phenothiazine Unclear Promazine [2]
MR002781 Promazine Promazine 5-sulfoxide Oxidation - 5-Sulphoxidation Promazine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002780 3-hydroxypromazine 3-hydroxypromazine glucuronide Conjugation - Glucuronidation Promazine [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development Curr Med Chem. 2009;16(27):3480-675. doi: 10.2174/092986709789057635.
2 Hazardous Substances Data Bank:Promazine

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