Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002849)
Formula
SVG example
Reactant Epinephrine hydrochloride Product Dihydroxymandelic acid
Reactant Info Product Info
Metabolic Enzyme Monoamine oxidase type A (MAO-A) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002847 Epinephrine hydrochloride Epinephrine glucuronide metabolite Conjugation - Glucuronidation Epinephrine hydrochloride [1]
MR002846 Epinephrine hydrochloride Epinephrine sulfate metabolite Conjugation - Sulfation Epinephrine hydrochloride [2]
MR002848 Epinephrine hydrochloride Metanephrine Conjugation - O-Methylation Epinephrine hydrochloride [3]
References
1 LABEL:?ARTICAINE HYDROCHLORIDE AND EPINEPHRINE injection, solution
2 Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate. Biochem Biophys Res Commun. 2005 Sep 23;335(2):417-23.
3 Different metabolism of norepinephrine and epinephrine by catechol-O-methyltransferase and monoamine oxidase in rats. J Pharmacol Exp Ther. 1994 Mar;268(3):1242-51.

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