Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003052)
Formula Reactant Atazanavir metabolite M2 Product Atazanavir metabolite M6
Reactant Info Product Info
Metabolic Type Other reaction - Monodehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003047 Atazanavir Atazanavir metabolite M2 Oxidation - Monohydroxylation Atazanavir [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003050 Atazanavir metabolite M2 Atazanavir metabolite M10 Oxidation - Dihydroxylation Atazanavir [1]
MR003054 Atazanavir metabolite M2 Atazanavir metabolite M12 Unclear Atazanavir [1]
MR003053 Atazanavir metabolite M2 Atazanavir metabolite M7 Other reaction - Monodehydrogenation Atazanavir [1]
MR003048 Atazanavir metabolite M2 Atazanavir metabolite M8 Unclear Atazanavir [1]
References
1 CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism Drug Metab Dispos. 2011 Mar;39(3):394-401. doi: 10.1124/dmd.110.036327.

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