Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003069)
Formula Reactant Spermine Product N-AcSpm
Reactant Info Product Info
Metabolic Enzyme Permidine/putrescine ABC transporter substrate-binding protein (BleG1_1835) DME Info
Spermidine N(1)-acetyltransferase (speG) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000578 CCG-205124 Spermine Unclear CCG-205124 [1]
MR007653 Putrescine Spermine Other reaction - Decarboxylation Putrescine [2]
MR003068 Spermidine Spermine Unclear Agmatine [3], [4], [5]
MR012736 Spermidine Spermine Unclear - Unclear Arginine [6]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000575 Spermine N--Acetylspermine Unclear CCG-205124 [1]
References
1 The Association between Spermidine/Spermine N(1)-Acetyltransferase (SSAT) and Human Malignancies Int J Mol Sci. 2022 May 25;23(11):5926. doi: 10.3390/ijms23115926.
2 Human aldehyde dehydrogenase: metabolism of putrescine and histamine
3 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
4 Genome-wide analysis of polyamine biosynthesis genes in wheat reveals gene expression specificity and involvement of STRE and MYB-elements in regulating polyamines under drought. BMC Genomics. 2022 Oct 30;23(1):734. doi: 10.1186/s12864-022-08946-2.
5 Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 Mar 25;12(4):501. doi: 10.3390/biom12040501.
6 Arginine Metabolism Revisited

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