Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003123)
Formula
SVG example
Hydrolysis
Reactant Acebutolol Product Acetolol
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 2 (CES2) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003124 Acebutolol N-hydroxy acetolol Oxidation - Hydroxylation Acebutolol [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003122 Acetolol Diacetolol Conjugation - Acetylation Acebutolol [2]
References
1 U. S. FDA Label - Acebutolol
2 Evaluation of drug-drug interactions via inhibition of hydrolases by orlistat, an anti-obesity drug. Drug Metab Dispos. 2023 May 3:DMD-AR-2023-001266. doi: 10.1124/dmd.123.001266.

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