Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR003124)
Formula	CYP2C19 Hydroxylation
	Reactant	Acebutolol		Product	N-hydroxy acetolol
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Mephenytoin 4-hydroxylase (CYP2C19)					DME Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003123	Acebutolol	Acetolol	Hydrolysis - Hydrolysis	Acebutolol	[1], [2]

References
1	It is our problem too ASDC J Dent Child. 1979 May-Jun;46(3):184.
2	Evaluation of drug-drug interactions via inhibition of hydrolases by orlistat, an anti-obesity drug. Drug Metab Dispos. 2023 May 3:DMD-AR-2023-001266. doi: 10.1124/dmd.123.001266.

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