Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003234)
Formula
SVG example
Demethylation
Reactant Deoxydaunorubicinol aglycone Product Demethyl deoxydaunorubicinol aglycone
Reactant Info Product Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003231 Daunorubicinol Deoxydaunorubicinol aglycone Hydrolysis - Hydrolysis Daunorubicin [1]
MR003240 Deoxydaunorubicin aglycone Deoxydaunorubicinol aglycone Reduction - Reduction Daunorubicin [1]
MR003233 Deoxydaunorubicinol aglycone Deoxydaunorubicinol aglycone Reduction - Reduction Daunorubicin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003235 Deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone-4-O-beta-glucuronide metabolite Conjugation - Glucuronidation Daunorubicin [1]
MR003236 Deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone-4-O-sulfate metabolite Conjugation - Sulfation Daunorubicin [1]
MR003233 Deoxydaunorubicinol aglycone Deoxydaunorubicinol aglycone Reduction - Reduction Daunorubicin [1]
MR003237 Deoxydaunorubicinol aglycone Deoxydaunorubicinol aglycone-13-O-beta-glucuronide Conjugation - Glucuronidation Daunorubicin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003238 Demethyl deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone-4-O-beta-glucuronide metabolite Conjugation - Glucuronidation Daunorubicin [1]
MR003239 Demethyl deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone-4-O-sulfate metabolite Conjugation - Sulfation Daunorubicin [1]
References
1 Daunorubicin metabolites in human urine J Pharmacol Exp Ther. 1975 Oct;195(1):41-9.

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