Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003240)
Formula
SVG example
Reduction
Reactant Deoxydaunorubicin aglycone Product Deoxydaunorubicinol aglycone
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003243 Daunorubicin Deoxydaunorubicin aglycone Hydrolysis - Hydrolysis Daunorubicin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003241 Deoxydaunorubicin aglycone Deoxydaunorubicinol aglycone-13-O-beta-glucuronide Conjugation - Glucuronidation Daunorubicin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003231 Daunorubicinol Deoxydaunorubicinol aglycone Hydrolysis - Hydrolysis Daunorubicin [2]
MR003233 Deoxydaunorubicinol aglycone Deoxydaunorubicinol aglycone Reduction - Reduction Daunorubicin [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003234 Deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone Oxidation - Demethylation Daunorubicin [2]
MR003235 Deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone-4-O-beta-glucuronide metabolite Conjugation - Glucuronidation Daunorubicin [2]
MR003236 Deoxydaunorubicinol aglycone Demethyl deoxydaunorubicinol aglycone-4-O-sulfate metabolite Conjugation - Sulfation Daunorubicin [2]
MR003233 Deoxydaunorubicinol aglycone Deoxydaunorubicinol aglycone Reduction - Reduction Daunorubicin [2]
MR003237 Deoxydaunorubicinol aglycone Deoxydaunorubicinol aglycone-13-O-beta-glucuronide Conjugation - Glucuronidation Daunorubicin [2]
References
1 U. S. FDA Label -Daunorubicin
2 Daunorubicin metabolites in human urine J Pharmacol Exp Ther. 1975 Oct;195(1):41-9.

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