Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003349)
Formula Reactant Apalutamide metabolite M10 Product Apalutamide metabolite M12
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003362 Apalutamide Apalutamide metabolite M10 Conjugation - Cysteine-Glycine Condensation Apalutamide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003350 Apalutamide metabolite M10 Apalutamide metabolite M9 Conjugation - Cysteine Condensation Apalutamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003343 N-desmethyl apalutamide Apalutamide metabolite M12 Unclear Apalutamide [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003347 Apalutamide metabolite M12 Apalutamide metabolite M14 Unclear Apalutamide [1]
References
1 Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes Drug Metab Dispos. 2019 May;47(5):453-464. doi: 10.1124/dmd.118.084517.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.