Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003660)
Formula Reactant INCB-024360 Metabolite M11 Product INCB-024360 Metabolite M12
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003659 INCB-024360 INCB-024360 Metabolite M11 Unclear INCB-024360 [1]
References
1 Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.