Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003765)
Formula Reactant MK-0859 Metabolite M2 Product MK-0859 Metabolite M9
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003764 MK-0859 Metabolite M1 MK-0859 Metabolite M2 Oxidation - Hydrolyzationn MK-0859 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003766 MK-0859 Metabolite M2 MK-0859 Metabolite M5 Conjugation - Glucuronidation MK-0859 [2]
MR003767 MK-0859 Metabolite M2 MK-0859 Metabolite M7 Conjugation - Glucuronidation MK-0859 [2]
References
1 Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
2 Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

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