Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003767)
Formula Reactant MK-0859 Metabolite M2 Product MK-0859 Metabolite M7
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003764 MK-0859 Metabolite M1 MK-0859 Metabolite M2 Oxidation - Hydrolyzationn MK-0859 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003766 MK-0859 Metabolite M2 MK-0859 Metabolite M5 Conjugation - Glucuronidation MK-0859 [2]
MR003765 MK-0859 Metabolite M2 MK-0859 Metabolite M9 Conjugation - Glutathione conjugation MK-0859 [2]
References
1 Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
2 Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

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