Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003815)
Formula Reactant AG-1549 Product AG-1549 Metabolite C26
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A1 (Cyp3a1) DME Info
Cytochrome P450 3A2 (Cyp3a2) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003811 AG-1549 AG-1549 Metabolite C19 Oxidation - Oxidationn AG-1549 [1]
MR003796 AG-1549 AG-1549 Metabolite C23 Oxidation - Oxidationn AG-1549 [1]
MR003818 AG-1549 AG-1549 Metabolite C27 Unclear AG-1549 [1]
MR003821 AG-1549 AG-1549 Metabolite C20 Oxidation - Oxidationn AG-1549 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003816 AG-1549 Metabolite C26 AG-1549 Metabolite C12 Unclear AG-1549 [1]
MR003817 AG-1549 Metabolite C26 AG-1549 Metabolite C15 Oxidation - Oxidationn AG-1549 [1]
References
1 Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.