Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003852)
Formula
SVG example
Reactant LCA Product Murideoxycholic acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C70 (Cyp2c70) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003853 Bile acid LCA Unclear Bile acid [1]
MR002540 Chenodeoxycholic acid Lithocholic acid Unclear Chenodeoxycholic acid [2]
MR002483 Ursodeoxycholic acid Lithocholic acid Unclear Ursodeoxycholic acid [3]
MR003850 UDCA LCA Unclear Bile acid [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003851 LCA Hyodexycholic acid Unclear Bile acid [1]
References
1 Bile Acid Metabolism in Liver Pathobiology
2 Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. Drug Metab Dispos. 2008 Oct;36(10):1983-91.
3 Pharmacology of ursodeoxycholic acid, an enterohepatic drug Scand J Gastroenterol Suppl. 1994;204:1-15. doi: 10.3109/00365529409103618.

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