Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003976)
Formula Reactant SGX-523 Product 2-quinolinone-SGX523
Reactant Info Product Info
Metabolic Enzyme Aldehyde oxidase (AOX1) DME Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003977 2-quinolinone-SGX523 N-desmethyl 2-quinolinone-SGX523 Oxidation - N-demethylation SGX-523 [1]
References
1 Species-specific metabolism of SGX523 by aldehyde oxidase and the toxicological implications. Drug Metab Dispos. 2010 Aug;38(8):1277-85.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.