Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004519)
Formula Reactant WIN 55212-2 Product WIN 55212-2 Metabolite M1a
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004523 WIN 55212-2 WIN 55212-2 Metabolite M1b Oxidation - Oxidationn WIN 55212-2 [1]
MR004508 WIN 55212-2 WIN 55212-2 Metabolite M1c Oxidation - Hydrolyzationn WIN 55212-2 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004528 WIN 55212-2 Metabolite M1a WIN 55212-2 Metabolite M2a Oxidation - Hydrolyzationn WIN 55212-2 [1]
MR004526 WIN 55212-2 Metabolite M1a WIN 55212-2 Metabolite M3a Oxidation - Hydrolyzationn WIN 55212-2 [1]
MR004527 WIN 55212-2 Metabolite M1a WIN 55212-2 Metabolite M3b Unclear WIN 55212-2 [1]
MR004520 WIN 55212-2 Metabolite M1a WIN 55212-2 Metabolite M8a Oxidation - Hydrolyzationn WIN 55212-2 [2], [1]
References
1 Toxicokinetics of new psychoactive substances: plasma protein binding, metabolic stability, and human phase I metabolism of the synthetic cannabinoid WIN 55,212-2 studied using in vitro tools and LC-HR-MS/MS
2 In vitro metabolism of R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a cannabinoid receptor agonist

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