Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004537)
Formula
SVG example
Reactant AC-12166 Product Androst-4-ene-3,17-dione (4ADN)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004534 AC-12166 Testosterone Unclear AC-12166 [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003149 Dehydroepiandrosterone 4-androstene-3,17-dione(AD) Unclear Dehydroepiandrosterone [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003145 4-androstene-3,17-dione(AD) Estradiol-17 beta Unclear Dehydroepiandrosterone [3]
MR003147 4-androstene-3,17-dione(AD) Estrone Unclear Dehydroepiandrosterone [3]
MR003146 4-androstene-3,17-dione(AD) Testosterone Unclear Dehydroepiandrosterone [3]
References
1 Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat
2 Conversion of 4-androstenediol and 5-androstenediol to testosterone, and conversion of dehydroepiandrosterone to 4-androstenediol by rat testis in vitro
3 Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation Front Pharmacol. 2018 Jul 10;9:742. doi: 10.3389/fphar.2018.00742.

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