Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004660)
Formula
CYP3A4 ...
SVG example
Reactant Ifosfamide Product Chloroacetaldehyde
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004662 Ifosfamide 3-Dechloroethylifosfamide Unclear Ifosfamide [1], [2]
MR004650 Ifosfamide 4-Hydroxyifosfamide Oxidation - 4-hydroxylation Ifosfamide [2]
MR004663 Ifosfamide Dechloroethylifosfamide Unclear Ifosfamide [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012908 Cyclobenzaprine Chloroacetaldehyde Unclear Cyclobenzaprine [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004661 Chloroacetaldehyde 2-chloroethanol Oxidation - Oxidationn Ifosfamide [4]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
2 The KEGG resource for deciphering the genome
3 U. S. FDA Label -Cyclobenzaprine
4 DrugBank(Pharmacology-Metabolism):Ifosfamide

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