Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004839)
Formula
SVG example
Reduction
Reactant 4-(6-Hydroxy-2-naphthyl)- butan-2-one Product 4-(6-hydroxy-2-naphthyl)- butan-2-ol
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004838 Nabumetone 4-(6-Hydroxy-2-naphthyl)- butan-2-one Oxidation - O-demethylation Nabumetone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004846 4-(6-Hydroxy-2-naphthyl)- butan-2-one 4-(6-Hydroxy-2-naphthyl)- butan-2-one glucuronide Conjugation - O-glucuronidation Nabumetone [1]
MR004849 4-(6-Hydroxy-2-naphthyl)- butan-2-one 4-(6-Hydroxy-2-naphthyl)- butan-2-one sulfate Conjugation - Sulfonation Nabumetone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004833 4-(6-Methoxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol Unclear Nabumetone [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004834 4-(6-hydroxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol glucuronide (2-OH conjugated) Conjugation - O-glucuronidation Nabumetone [1]
MR004836 4-(6-hydroxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol glucuronide (6-OH conjugated) Conjugation - O-glucuronidation Nabumetone [1]
MR004845 4-(6-hydroxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol sulfate Conjugation - Sulfonation Nabumetone [1]
References
1 Clinical pharmacokinetics of nabumetone. The dawn of selective cyclo-oxygenase-2 inhibition?

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.