Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005049)
Formula
AMS
SVG example
Reactant Flutamide Product Flutamide Metabolite M3
Reactant Info Product Info
Metabolic Enzyme Amidase (AMS) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005053 Flutamide Flutamide Metabolite M1 Unclear Flutamide [1]
MR005055 Flutamide Flutamide Metabolite M2 Unclear Flutamide [1]
MR005045 Flutamide Flutamide Metabolite M9 Unclear Flutamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007734 Hydroxyflutamide Hydroxyflutamide metabolite Flu-1 Unclear - Unclear Hydroxyflutamide [2]
MR007730 Hydroxyflutamide metabolite M1 Hydroxyflutamide metabolite Flu-1 Unclear - Unclear Hydroxyflutamide [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005052 Flutamide Metabolite M3 Flutamide Metabolite M4 Unclear Flutamide [1]
MR005050 Flutamide Metabolite M3 Flutamide Metabolite M5 Unclear Flutamide [1]
MR014049 Hydroxyflutamide metabolite Flu-1 Hydroxyflutamide metabolite Flu-3 Unclear - Unclear Hydroxyflutamide [2]
References
1 Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites
2 Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry

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