Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005050)
Formula
SVG example
Reactant Flutamide Metabolite M3 Product Flutamide Metabolite M5
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005049 Flutamide Flutamide Metabolite M3 Unclear Flutamide [1]
MR007734 Hydroxyflutamide Hydroxyflutamide metabolite Flu-1 Unclear - Unclear Hydroxyflutamide [2]
MR007730 Hydroxyflutamide metabolite M1 Hydroxyflutamide metabolite Flu-1 Unclear - Unclear Hydroxyflutamide [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005052 Flutamide Metabolite M3 Flutamide Metabolite M4 Unclear Flutamide [1]
MR014049 Hydroxyflutamide metabolite Flu-1 Hydroxyflutamide metabolite Flu-3 Unclear - Unclear Hydroxyflutamide [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005051 Flutamide Metabolite M5 Flutamide Metabolite M6 Conjugation - Sulfation Flutamide [1]
References
1 Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites
2 Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.