Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005455)
Formula Reactant Capmatinib Product Capmatinib M26
Reactant Info Product Info
Metabolic Type Reduction - Hydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005461 Capmatinib Capmatinib M13 Unclear Capmatinib [1]
MR005464 Capmatinib Capmatinib M16 Unclear Capmatinib [1]
MR005450 Capmatinib Capmatinib M18 Unclear Capmatinib [1]
MR005466 Capmatinib Capmatinib M19 Unclear Capmatinib [1]
MR005467 Capmatinib Capmatinib M21 Unclear Capmatinib [1]
MR005468 Capmatinib Capmatinib M41 Unclear Capmatinib [1]
MR005469 Capmatinib Capmatinib M48 Unclear Capmatinib [1]
MR005465 Capmatinib Capmatinib M8 Unclear Capmatinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005456 Capmatinib M26 Capmatinib M27 Reduction - Hydrogenation Capmatinib [1]
MR005460 Capmatinib M26 Capmatinib M33 Reduction - Hydrogenation Capmatinib [1]
MR005458 Capmatinib M26 Capmatinib M37 Reduction - Hydrogenation Capmatinib [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite

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